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What is LubriSyn?

LubriSyn is an oral form of hyaluronic acid (HA) administered daily to maintain consistent levels in the body. LubriSyn can help maintain healthy joints by improving the quality of synovial fluid, the liquid that surrounds the horse’s joints and helps cartilage function.

What is LubriSyn made from?

Unlike other hyaluronic acid (HA) products made from things such as rooster combs, LubriSyn is extracted from a microbial source. This method keeps it free from dermatan, chondroitin sulfate and other glycosaminoglycan contamination that may be found in other HA products.

How is LubriSyn administered?

LubriSyn is the only patented oral form of HA. It has been proven that HA needs to be in a liquid state in order to have the highest absorption levels in the body.

What are Adequan® and Legend®?

Both products are drugs approved by the Food and Drug Administration to treat arthritis or joint inflammation and are administered by injection. Legend is hyaluronic acid formulated for intravenous or intramuscular use. Adequan is polysulfated chondroitin sulfate also formulated for intramuscular use. Both products result in a rise in blood concentration after administration followed by a return to baseline levels within several hours unless the drug is re-administered (Popot et al., 2004)

Is LubriSyn like Cosequin®?

No. Cosequin is mainly made up of glucosamine and chondroitin sulfate. Cosequin works on the cartilage while LubriSyn is more beneficial to the joint fluid. These two products can work synergistically to improve the joint integrity.

How much should I give?

Both the pints and the quarts have a measuring reservoir that is marked in milliliters and ounces. We recommend that you start with a “loading” dose for three to four days of 30 ml or 1 oz. Then you can drop it to the “maintenance” dose of 15 ml or 1/2 oz. These measurements can vary slightly from animal to animal. The gallon size comes with a pump that can be placed directly in the container. Each “squirt” is a measured 15 ml dose. The other option for the gallon is the dosing gun. It also fits right on the gallon and administers a measured dose directly into the animal’s mouth.

How can LubriSyn benefit my animal?

LubriSyn allows the joints to maintain health by quickly increasing mobility and joint stability. This translates into an increase in performance in the animal.

Is there proof that it gets to the joint?

There have been no studies completed to date that show increases of HA in the joints after administration of an HA supplement. These types of studies are extremely invasive to the joints as well as difficult on the animal. There are existing studies that show marked improvement in animals’ mobility and performance while undergoing HA supplementation.

What does LubriSyn taste and smell like?

LubriSyn is basically an odorless and tasteless product. Since LubriSyn is a sodium-based product, some people say that it does have a slightly salty taste.

Can I give too much?

Our safety studies have shown that even at five times the recommended dose for 90 days straight there were no adverse effects. These studies compared a placebo to Lubrisyn at either three or five times the recommended level of 15Mls. Because LubriSyn is a naturally occurring substance made by the body, we have not had any adverse effects reported from dosing levels.

How long before I will see results?

There is no exact time. Most animals observed have improved noticeably within seven to 14 days. Results vary depending on severity of the joint health problems and the dose of LubriSyn.

How much does it cost?

LubriSyn comes in several different sizes. The pint provides a one-month supply for one horse and costs $66.00—that is only $2.20 per day. The quart is a two-month supply for one horse for $122.00. This reduces your daily cost to $2.00 per day. The most economical way to buy LubriSyn for anyone treating multiple horses is by the gallon. By purchasing the gallon you are essentially buying three quarts and getting one free. The gallons are $350.00, which brings the daily cost down to $1.37 per day per horse.

Will my animal object to LubriSyn administration?

So far we know of no problems with animals accepting LubriSyn. Many people just administer with grain. Others feel more comfortable using the dosing gun placed directly in the animal’s mouth.

Will LubriSyn go bad?

This product may break down if contaminated by bacteria. We have added a minimal amount of preservatives to try to avoid any deterioration of the product. We have also taken steps through our administering methods (i.e., the squeeze-filled reservoir on the pints and quarts, and the pump and dosing gun for the gallons) to ensure its integrity. These methods were chosen to try to keep the unused portion of the product in as clean an environment as possible.

Will extreme temperatures hurt LubriSyn?

Yes. As with most liquid nutritional supplements, extreme hot or cold temperatures can cause some breakdown. We recommend storing LubriSyn in the range between 40 and 90 degrees Fahrenheit. DO NOT freeze LubriSyn.

Will LubriSyn create a test positive?

No. HA is something found in the body naturally and it will not show up in a post-competition test. However, if competing under “zero supplement” regulations (e.g., FEI), the horse will not suffer any ill effects of LubriSyn withdrawal during the few days of competition.

Popot, MA, Bonnaire Y, Guechot J, Toutain PL (2004) Hyaluronan in horses: physiological production rate, plasma and synovial fluid concentrations in control conditions and following sodium hyaluronate administration, Equine Vet J., 36(6): 482-7.