Learn how to support the naturally-occurring hyaluronic acid (HA) that helps lubricate and cushion joints for comfort and easy movement.

LubriSyn has been the gold standard in joint support for over 20 years
Hyaluronic acid (HA) is a naturally-occurring substance in animals that retains water, refreshes synovial fluid, and helps cushion joints.
Our expert-developed, safe and natural liquid formula offers rapid, lasting joint support without needles or hassle.
Oral delivery in liquid form maximizes absorption compared to powder, providing more support per dose.
Using a naturally-occurring substance as its only active ingredient, LubriSyn helps support mobility and productivity for years to come.
Daily use helps people, pets, and large animals stay active, agile, and comfortable while minimizing future costly interventions.
Added MSM provides dual-action support to lubricate joints and help reduce inflammation, stiffness, and discomfort.
Both formulas are crafted with the same high standards of purity and safety. Choose original LubriSyn or MSM fortified to fit your needs.

Get the joint support you deserve with the power of LubriSyn. Keep your joints moving freely with a natural daily supplement trusted by professionals, because every step matters.
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This formula combines high-molecular-weight hyaluronic acid (HA) with MSM (methylsulfonylmethane) to provide powerful, dual-action support for lubricating joints, helping reduce inflammation, stiffness, and discomfort.
Shop NowThis table outlines four commonly included joint nutrition ingredients with descriptions intended for general educational purposes.
Hyaluronic Acid (HA) | MSM (methylsulfonyl-methane) | Glucosamine* | Chondroitin* | |
|---|---|---|---|---|
What it is | A naturally occurring substance found in joints and connective tissues | An organic sulfur compound found in foods and the human body | An amino sugar naturally present in cartilage | A complex carbohydrate found in cartilage |
Role in joint nutrition | Supports fluid in joint spaces and connective structures | Provides dietary sulfur, which is a component of structural proteins | A building block in certain structural molecules | Part of long chain molecules in structural tissues |
Common forms in supplements | Liquid/powder/pill/chew | Capsule/powder, liquid | Capsule/pill, powder | Capsule/pill, powder |
Scientific origins | Often sourced from bacterial fermentation or rooster combs; different molecular weights may appear in products | Synthetically produced through crystallization, making it vegan; may be paired with other joint ingredients | Sulfate form may include additional sulfate; vegetarian versions available | Usually derived from animal cartilage (e.g., bovine, porcine); purity can vary |
| *LubriSyn does not contain the following ingredient typically found in other joint supplements. | *LubriSyn does not contain the following ingredient typically found in other joint supplements. |

We pay close attention to every detail of our products, from molecular weight to manufacturing quality and packaging. LubriSyn is made with high-quality, high-molecular-weight hyaluronic acid (HA). It’s made in the USA, produced in an FDA-approved facility, and is NSF certified, vegan, gluten-free, and BPA-free. Learn more about HA and its benefits in the research and studies below.
LubriSyn is made using a high-purity, bioidentical form of hyaluronic acid (HA). It is produced through a fermentation process involving bacteria rather than extraction from animal sources. This process helps create a consistent, stable HA that can be used in liquid form and focuses on maintaining molecular integrity to support its intended use in joint supplements.